Eligibility

The IMPACT-study is currently recruiting patients within the Lynch syndrome cohort. Please take a look at our Collaborators page to find out which genetic centres are taking part in the IMPACT-study.

Men are eligible for this study if they have,
  • been tested, and found to have, a BRCA1 or BRCA2 gene alteration (Cohort closed to recruitment),

OR

  • been tested, and found not to have a BRCA1 or BRCA2 gene alteration which is known to run in the family (Cohort closed to recruitment),
  • been tested, and found to have mutation within a Lynch syndrome gene (MLH1, MSH2 or MSH6),

OR

  • been tested, and found not to have a mutation within a Lynch syndrome gene (MLH1, MSH2 or MSH6) which is known to run in the family.
Participants in the study must also:
  • be aged between 40 and 69 years of age;
  • be of sufficiently good health to be able to participate in the study.
Men are unable to participate in this study if they have had:
  • a previous cancer which may affect their ability to participate (this can be discussed with the IMPACT study Coordinator);
  • a previous history of prostate cancer.

Men who have had a prostate biopsy for a raised PSA level should contact the IMPACT-study coordinator directly to discuss their eligibility for the study.

If you are interested in participating within the IMPACT study, please contact the study team to find out more about how you can participate within the study.

If you are a researcher and are interested in collaborating with the IMPACT study please contact the study team to find out more about  how you can collaborate with the study.